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MIB1 wt Allele
Human MIB1 wild-type allele is located in the vicinity of 18q11.2 and is approximately 130 kb in length. This allele, which encodes E3 ubiquitin-protein ligase MIB1 protein, plays a role in both ubiquitination and the regulation of Delta-mediated Notch signaling. (NCI Thesaurus)
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This gene is involved in both ubiquitination and cell signaling.
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