Health / Medical Topics |
Microtubule Stabilization
Microtubule Stabilization consists of activities involved in maintenance of filamentous tubes of variable length in the cytoskeleton composed primarily of conserved alpha, beta, and gamma tubulin that support movement of chromosomes or chromatids during mitosis and meiosis; and give shape, structure, and organization to the cytoplasm and to a cell. (NCI Thesaurus)
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Any cytoskeletal process involving microtubule structures and their associated proteins.
Microtubule polymerization is a cellular process typically, though not solely, involved in cell motility and cell division. Stabilization of microtubule polymerization…
Microtubule structures are disassembled and re-assembled during mitosis to achieve the final state of cell division. Microtubule dynamic alteration involves an…
Any microtubule process involving the removal of tubulin heterodimers from one or both ends of a microtubule.
It is the aggregated products of microtubules during mitosis where chromosomes line up prior to the segregation process. Many antineoplastic agents cause…
Proteins associated with the microtubule assembly infrastructure. These proteins include specialized motor proteins (dynein and kinesin) and smaller tubulin-crosslinking proteins (tau…