| Health / Medical Topics |
Microtubule-targeted Agent BAL101553
An orally available, highly water-soluble lysine prodrug of the synthetic small molecule BAL27862 with potential antitumor activity. Upon administration of BAL101553 and conversion into the active form BAL27862, this agent binds to tubulin at a site distinct from the vinca-alkaloid-binding site, and prevents tubulin polymerization and destabilizes microtubules, ultimately leading to cell cycle arrest, blockage of cell division and an induction of cell death in cancer cells. (NCI Thesaurus)
YOU MAY ALSO LIKE
Microtubule-associated serine/threonine-protein kinase 2 (1798 aa, ~196 kDa) is encoded by the human MAST2 gene. This protein is involved in both cytoskeletal…
Microtubule-associated serine/threonine-protein kinase 1 (1570 aa, ~180 kDa) is encoded by the human MAST1 gene. This protein plays a role in serine/threonine…
Microtubule-associated proteins 1A/1B light chain 3A (121 aa, ~14 kDa) is encoded by the human MAP1LC3A gene. This protein plays a role…
Microtubule-associated proteins 1A/1B light chain 3-II proteins (LC3-II) are products of the autophagy-dependent processing of microtubule-associated proteins 1A/1B light chain 3 family…
A protein family whose members bind to microtubule-associated protein 1A and 1B and are involved in the formation of autophagosomes.
Microtubule-associated protein, RP/EB family, member 1 protein is a cellular division process protein that is encoded by the human MAPRE1 gene and…
