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Middle Ear Cholesteatoma
Definition 1
A non-neoplastic lesion characterized by the proliferation of keratinizing squamous epithelium in the middle ear that results in the accumulation of keratin and cells. It is usually caused by repeated infections. If left untreated, it may increase in size and destroy the adjacent delicate bones of the middle ear. (NCI Thesaurus)
Definition 2
Cholesteatoma of the middle ear, usually associated with chronic infection, and commonly affecting the tympanum, epitympanum, and antrum. (NLM, Medical Subject Headings)
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