Health / Medical Topics |
MIR451 wt Allele
The human MIR451 wild-type allele is located in the vicinity of 17q11.2 and is approximately 71 bases in length. This allele, which encodes MIR451 pre-miRNA, plays a role in the regulation of gene expression. Alteration in the expression of this gene is associated with development of breast cancer and glioblastoma. (NCI Thesaurus)
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