Health / Medical Topics

    Mirtazapine

    Pronunciation

    Definition 1

    A drug used to treat depression. Mirtazapine increases the levels of the chemicals serotonin and norepinephrine in the brain, which helps improve mood. It is a type of antidepressant. Also called Remeron. (NCI Dictionary)

    Definition 2

    A synthetic tetracyclic derivative of the piperazino-azepines with antidepressant activity. Although its mechanism of action is unknown, mirtazapine enhances central adrenergic and serotonergic transmission, possibly by acting as an antagonist at central presynaptic alpha 2 adrenergic inhibitory autoreceptors and heteroreceptors. This agent is a potent antagonist of 5-hydroxytryptamine type 2 (5-HT2), 5-HT3, and histamine 1 (H1) receptors, and a moderate antagonist of peripheral alpha 1 adrenergic and muscarinic receptors. (NCI Thesaurus)

    Definition 3

    A drug used to treat depression. It belongs to the family of drugs called antidepressant agents. (NCI Dictionary)




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