| Health / Medical Topics |
Mitochondrial DNA
Typically small, circular, intronless, and maternally inherited, mitochondrial DNA (mtDNA) is the multicopy deoxyribonucleic acid genome of mitochondria, intracellular organelles responsible for vital respiratory chain and oxidative phosphorylation reactions in higher eukaryotes. Replicated and transcribed by a separate enzymatic machinery from that of nuclear DNA, mtDNA encodes only a subset of mitochondrial functions. (NCI Thesaurus)
YOU MAY ALSO LIKE
Mitochondrial Damage involves any process that leads to dysfunction of mitochondria, whether by oxidative damage, mutation of mitochondrial DNA or other by…
A thin space between the outer and inner mitochondrial membranes formed by an invagination of the inner mitochondrial membrane.
Mitochondrial carrier homolog 2 (303 aa, ~33 kDa) is encoded by the human MTCH2 gene. This protein is involved in the modulation…
The oxidation of fatty acids is an important source of energy for ATP production in mitochondria through the entry of acetyl-CoA into…
Mitochondrial brown fat uncoupling protein 1 (307 aa, ~33 kDa) is encoded by the human UCP1 gene. This protein plays a role…
Mitochondria participate in apoptotic signaling pathways through the release of mitochondrial proteins into the cytoplasm. Cytochrome c, a key protein in electron…
