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Mitomycin Antineoplastic Antibiotic
Definition 1
Any of a class of anti-tumor antibiotics acting as alkylating agents. All mitomycins have the backbone of methyl, aziridine, pyrrolo, indole, and dione moieties. Bioreductively activated mitomycin antibiotics generate oxygen radicals and alkylate DNA, forming inter-strand cross-links and inhibiting DNA synthesis. (NCI Thesaurus)
Definition 2
An anticancer drug that belongs to the family of drugs called antitumor antibiotics. (NCI Dictionary)
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