MKL1/RBM15 Fusion Gene

A fusion gene that results from a chromosomal translocation t(1;22)(p13;q13) which fuses the 5' portion of the MKL1 gene to the 3' portion of the RBM15 gene. This rearrangement is associated with infantile acute megakaryoblastic leukemia. (NCI Thesaurus)

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MKL1 wt Allele

Human MKL1 wild-type allele is located in the vicinity of 22q13 and is approximately 226 kb in length. This allele, which encodes…

MKL1 Gene

This gene is involved in transcriptional modulation and muscle cell differentiation.

MKL/Myocardin-Like Protein 1

MKL/myocardin-like protein 1 (931 aa, ~99 kDa) is encoded by the human MKL1 gene. This protein is involved in both transcriptional activation…

MKI67 wt Allele

Human MKI67 wild-type allele is located within 10q25-qter and is approximately 30 kb in length. This allele, which encodes antigen KI-67 immunoprotein,…

MKI67 Gene

This gene is involved in cellular proliferation.

MKC-1

An orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabolites inhibit tubulin polymerization, blocking the formation…