MLH1 wt Allele

Human MLH1 wild-type allele is located in the vicinity of 3p21.3 and is approximately 57 kb in length. This allele, which encodes DNA mismatch repair protein Mlh1, plays a role in DNA mismatch repair. Aberrant alleles are associated with colon, endometrial and stomach cancers. Further, the defects in MLH1 are a cause of hereditary non-polyposis colorectal cancer. (NCI Thesaurus)

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MLH1 Protein

MLH1 protein is a DNA-binding, DNA-mismatch repair protein, of the MutL/HexB family, that dimerizes with PMS2 or MLH3. MLH1 is part…

MLH1 Gene

This gene plays a role in DNA mismatch repair.

MLF1 wt Allele

Human MLF1 wild-type allele is located in the vicinity of 3q25.1 and is approximately 36 kb in length. This allele, which encodes…

MLF1 Gene

This gene plays a role in both transcriptional regulation and cell cycle arrest.

MLANA wt Allele

Human MLANA wild-type allele is located in the vicinity of 9p24.1 and is approximately 20 kb in length. This allele, which encodes…

MLANA Gene

This gene plays a role in the development and maturation of melanosomes.