MLLT10/CLP1 Fusion Gene

A fusion gene that results from a complex chromosomal rearrangement invins(10;11)(p12;q23q12) which fuses the 5' end of the MLLT10 gene with the 3' end of the CLP1 gene. This chromosomal aberration is associated with acute monoblastic leukemia. (NCI Thesaurus)

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MLLT10 wt Allele

Human MLLT10 wild-type allele is located in the vicinity of 10p12 and is approximately 209 kb in length. This allele, which encodes…

MLLT10 Gene

This gene may be involved in transcriptional regulation.

MLLT1 wt Allele

Human MLLT1 wild-type allele is located in the vicinity of 19p13.3 and is approximately 70 kb in length. This allele, which encodes…

MLLT1 Gene

This gene is involved in transcriptional regulation and translocations in the gene are associated with acute leukemia.

MLL5 wt Allele

Human MLL5 wild-type allele is located in the vicinity of 7q22.1 and is approximately 100 kb in length. This allele, which encodes…

MLL5 Gene

This gene is involved in transcriptional regulation, cell cycle progression and protein methylation.