Health / Medical Topics |
MLLT10/PICALM Fusion Gene
A fusion gene that results from a chromosomal translocation t(10;11)(p13;q14) which fuses the 5' end of the MLLT10 gene to the extreme 3' end of the PICALM gene. This rearrangement is associated with both lymphoid and myeloid leukemia. (NCI Thesaurus)
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A fusion gene that results from a complex chromosomal rearrangement invins(10;11)(p12;q23q12) which fuses the 5' end of the MLLT10 gene with the…
Human MLLT10 wild-type allele is located in the vicinity of 10p12 and is approximately 209 kb in length. This allele, which encodes…
This gene may be involved in transcriptional regulation.
Human MLLT1 wild-type allele is located in the vicinity of 19p13.3 and is approximately 70 kb in length. This allele, which encodes…
This gene is involved in transcriptional regulation and translocations in the gene are associated with acute leukemia.
Human MLL5 wild-type allele is located in the vicinity of 7q22.1 and is approximately 100 kb in length. This allele, which encodes…