MLLT1 wt Allele

Human MLLT1 wild-type allele is located in the vicinity of 19p13.3 and is approximately 70 kb in length. This allele, which encodes protein ENL, plays a role in the activation of transcription by RNA polymerase II. Mixed-lineage leukemias are associated with the translocation t(11;19)(q23;p13.3) of the gene with the MLL gene. (NCI Thesaurus)

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MLLT1 Gene

This gene is involved in transcriptional regulation and translocations in the gene are associated with acute leukemia.

MLL5 wt Allele

Human MLL5 wild-type allele is located in the vicinity of 7q22.1 and is approximately 100 kb in length. This allele, which encodes…

MLL5 Gene

This gene is involved in transcriptional regulation, cell cycle progression and protein methylation.

MLL3 wt Allele

Human MLL3 wild-type allele is located in the vicinity of 7q36.1 and is approximately 302 kb in length. This allele, which encodes…

MLL3 Gene

This gene plays a role in both methylation and transcriptional regulation

MLL2 wt Allele

Human MLL2 wild-type allele is located within 12q12-q14 and is approximately 36 kb in length. This allele, which encodes myeloid/lymphoid or mixed-lineage…