| Health / Medical Topics |
MLLT3-MLL Fusion Protein Expression
Expression of a fusion protein that results from a t(9;11)(p22;q23) translocation, which involves the human genes MLL and MLLT3 and is associated with many leukemias. (NCI Thesaurus)
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Human MLLT3 wild-type allele is located in the vicinity of 9p22 and is approximately 281 kb in length. This allele, which encodes…
This gene plays a role in transcriptional regulation and translocations in the gene are associated with leukemia.
Human MLLT11 wild-type allele is located in the vicinity of 1q21 and is approximately 11 kb in length. This allele, which encodes…
This gene is involved in mitochondrial functions.
A fusion protein encoded by the MLLT10/PICALM fusion gene. This protein is comprised of the N-terminal zinc finger domain of protein AF-10…
A fusion gene that results from a chromosomal translocation t(10;11)(p13;q14) which fuses the 5' end of the MLLT10 gene to the extreme…
