| Health / Medical Topics |
MN1 wt Allele
Human MN1 wild-type allele is located in the vicinity of 22q11; 22q12.1 and is approximately 53 kb in length. This allele, which encodes probable tumor suppressor protein MN1, plays a role in tumor suppression. Mutation of the gene is associated with meningioma and a chromosomal translocation t(12;22)(p13;q11) of this gene and the ETV6 gene is associated with acute myeloid leukemia. (NCI Thesaurus)
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