| Health / Medical Topics |
MOAB B-3-CHX-A-DTPA
A monoclonal antibody B3, recognizing the tumor-associated Lewis Y antigen, is conjugated to a backbone-substituted derivative of DTPA, 2-(p-isothiocyanatobenzyl)-cyclohexyl-diethylenetriaminepentaacetic acid (CHX-A DTPA). DTPA is a bifunctional chelating agent thereby allowing for the binding of radioisotopes to the immunoconjugate. (NCI Thesaurus)
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