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    MODIFICATION

    Pronunciation (US): Play  (GB): Play

     I. (noun) 

    Sense 1

    Meaning:

    The act of making something different (as e.g. the size of a garment)play

    Synonyms:

    adjustment; alteration; modification

    Classified under:

    Nouns denoting acts or actions

    Hypernyms ("modification" is a kind of...):

    change (the action of changing something)

    Hyponyms (each of the following is a kind of "modification"):

    laxation; loosening (the act of making something less tight)

    tightening (the act of making something tighter)

    accommodation ((physiology) the automatic adjustment in focal length of the natural lens of the eye)

    adaptation ((physiology) the responsive adjustment of a sense organ (as the eye) to varying conditions (as of light))

    tune (the adjustment of a radio receiver or other circuit to a required frequency)

    Derivation:

    modify (cause to change; make different; cause a transformation)

    modify (make less severe or harsh or extreme)

    Sense 2

    Meaning:

    Slightly modified copy; not an exact copyplay

    Example:

    a modification of last year's model

    Classified under:

    Nouns denoting man-made objects

    Hypernyms ("modification" is a kind of...):

    copy (a thing made to be similar or identical to another thing)

    Derivation:

    modify (make less severe or harsh or extreme)

    Sense 3

    Meaning:

    An event that occurs when something passes from one state or phase to anotherplay

    Example:

    the neighborhood had undergone few modifications since his last visit years ago

    Synonyms:

    alteration; change; modification

    Classified under:

    Nouns denoting natural events

    Hypernyms ("modification" is a kind of...):

    happening; natural event; occurrence; occurrent (an event that happens)

    Hyponyms (each of the following is a kind of "modification"):

    increase (a change resulting in an increase)

    easing; moderation; relief (a change for the better)

    deformation (alteration in the shape or dimensions of an object as a result of the application of stress to it)

    transition (a change from one place or state or subject or stage to another)

    shift; transformation; transmutation (a qualitative change)

    scintillation; sparkling; twinkle (a rapid change in brightness; a brief spark or flash)

    play; shimmer (a weak and tremulous light)

    transmutation ((physics) the change of one chemical element into another (as by nuclear decay or radioactive bombardment))

    damage; harm; impairment (the occurrence of a change for the worse)

    development (a recent event that has some relevance for the present situation)

    revolution (a drastic and far-reaching change in ways of thinking and behaving)

    chromosomal mutation; genetic mutation; mutation ((genetics) any event that changes genetic structure; any alteration in the inherited nucleic acid sequence of the genotype of an organism)

    sex change (a change in a person's physical sexual characteristics (as by surgery and hormone treatments))

    loss of consciousness (the occurrence of a loss of the ability to perceive and respond)

    acceleration (an increase in rate of change)

    deceleration; retardation; slowing (a decrease in rate of change)

    avulsion (an abrupt change in the course of a stream that forms the boundary between two parcels of land resulting in the loss of part of the land of one landowner and a consequent increase in the land of another)

    break (an abrupt change in the tone or register of the voice (as at puberty or due to emotion))

    mutation (a change or alteration in form or qualities)

    sublimation ((psychology) modifying the natural expression of an impulse or instinct (especially a sexual one) to one that is socially acceptable)

    surprise (a sudden unexpected event)

    birth; nascence; nascency; nativity (the event of being born)

    breakup; detachment; separation (coming apart)

    vagary (an unexpected and inexplicable change in something (in a situation or a person's behavior, etc.))

    fluctuation; variation (an instance of change; the rate or magnitude of change)

    conversion (a change of religion)

    death; decease; expiry (the event of dying or departure from life)

    decrease; drop-off; lessening (a change downward)

    destabilization (an event that causes a loss of equilibrium (as of a ship or aircraft))

    Derivation:

    modify (make less severe or harsh or extreme)

    Sense 4

    Meaning:

    The grammatical relation that exists when a word qualifies the meaning of the phraseplay

    Synonyms:

    limiting; modification; qualifying

    Classified under:

    Nouns denoting relations between people or things or ideas

    Hypernyms ("modification" is a kind of...):

    grammatical relation (a linguistic relation established by grammar)

    Hyponyms (each of the following is a kind of "modification"):

    restrictiveness (a grammatical qualification that makes the meaning more specific ('red hat' has a more specific meaning than 'hat'))

    apposition (a grammatical relation between a word and a noun phrase that follows)

    Derivation:

    modify (add a modifier to a constituent)

    Credits

     Context examples: 

    This allele, which encodes ubiquitin-conjugating enzyme E2 R1 protein, is involved in the modification of ubiquitin.

    (CDC34 wt Allele, NCI Thesaurus)

    This protein may be involved in post-translational protein modification.

    (Mono-ADP-Ribosyltransferase Sirtuin-6, NCI Thesaurus)

    This gene is involved in the modification of spinal muscular atrophy.

    (NAIP Gene, NCI Thesaurus)

    This gene plays a role in protein post-translational modification.

    (NEDD8 Gene, NCI Thesaurus)

    This gene is involved in arginine modification.

    (PADI4 Gene, NCI Thesaurus)

    JAK2 is the most common mutated gene in bcr-abl-negative myeloproliferative disorders; the JAK2V617F gain-of-function mutation involves a valine-to-phenylalanine modification at position 617.

    (Momelotinib, NCI Thesaurus)

    A variation in or modification of the molecular sequence of a gene or gene product.

    (Molecular Sequence Variation, NCI Thesaurus)

    It refers to amino acid residue within a peptide that accepts fatty acid, palmitoyl group (C15H31-)as one of the reversible post-translational modifications.

    (Palmitic Acylation Site, NCI Thesaurus)

    Any type of stress response signaling that results in modification to the process of cell death.

    (Cell Death Signaling Process, NCI Thesaurus)

    This protein plays a role in chromatin modification.

    (Metastasis-Associated Protein MTA2, NCI Thesaurus)


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