Library / English Dictionary

MONOCLONAL

Pronunciation (US):

(GB):

 I. (noun) 

Sense 1

Meaning:

Any of a class of antibodies produced in the laboratory by a single clone of cells or a cell line and consisting of identical antibody molecules

Synonyms:

monoclonal; monoclonal antibody

Classified under:

Nouns denoting substances

Hypernyms ("monoclonal" is a kind of...):

antibody (any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response)

Hyponyms (each of the following is a kind of "monoclonal"):

infliximab; Remicade (a monoclonal antibody (trade name Remicade) used to treat Crohn's disease and rheumatoid arthritis; administered by infusion; use and dosage must be determined by a physician)

 II. (adjective) 

Sense 1

Meaning:

Forming or derived from a single clone

Classified under:

Relational adjectives (pertainyms)

Pertainym:

clone (a group of genetically identical cells or organisms derived from a single cell or individual by some kind of asexual reproduction)

Credits

 Context examples: 

A monoclonal antibody is made so that it binds to only one substance.

(Monoclonal antibody, NCI Dictionary)

A nonspecific monoclonal antibody Fab fragment for murine leukemia virus (MuLV) 1.4.

(Monoclonal Antibody 1.4 F(ab), NCI Thesaurus)

A murine monoclonal anti-idiotype antibody (anti-Id).

(Monoclonal Antibody 11D10, NCI Thesaurus)

Also called lintuzumab and monoclonal antibody HuM195.

(MoAb HuM195, NCI Dictionary)

Also called anti-IGF1R recombinant monoclonal antibody MK-0646.

(MK-0646, NCI Dictionary)

Also called anti-CCR2 monoclonal antibody MLN1202.

(MLN1202, NCI Dictionary)

Also called Ch14.18 and monoclonal antibody Ch14.18.

(MOAB Ch14.18, NCI Dictionary)

A type of monoclonal antibody used in the treatment of leukemia.

(Alemtuzumab, NCI Dictionary)

A human monoclonal antibody that is being used to treat colorectal cancer that has spread to other parts of the body.

(ABX-EGF, NCI Dictionary)

The researchers evaluated one of these promising monoclonal anti-HIV antibodies in people.

(HIV Immunotherapy Promising in First Human Study, NIH)