Health / Medical Topics |
Monoclonal Antibody 2A11
A recombinant, murine monoclonal antibody directed against gastrin-releasing peptide, one of a number of bombesin-like peptides (BLP). Tumor cells, such as small cell lung cancer (SCLC) cells, express and secrete BLP that activate specific cell growth-promoting receptors. Monoclonal antibody 2A11 has been shown to decrease the growth of SCLC cells in vitro and in animal models. (NCI Thesaurus)
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