| Health / Medical Topics |
Monoclonal Antibody 48.7 F(ab)
A Fab fragment of the mouse monoclonal antibody (MoAb) 48.7. MoAb 48.7 Fab (fragment antigen binding) recognizes proteoglycan antigen expressed on the cell surface of melanoma cells. The Fab fragments are obtained through papain digestion in the presence of cysteine. The advantage of using MoAb 48.7 Fab fragments over whole antibodies is that they have reduced immunogenicity, better penetration of tissues, rapid clearance from the body and that they do not induce precipitation. (NCI Thesaurus)
YOU MAY ALSO LIKE
A mouse monoclonal antibody (MoAb) with proteoglycan antigen detection and binding activity. Hybridomas of SP2/0 mouse myeloma cells and mouse spleen cells…
A synthetic antibody targeted against a cell surface glycoprotein (gp74) on a human c-Ha-ras oncogene transformed cell line. Monoclonal Antibody 45-2D9…
A recombinant monoclonal antibody in which the heavy and light chain variable domains mimic a specific epitope of the tumor-associated protein carcinoembryonic…
A murine monoclonal antibody directed against the cell-surface, tumor-associated antigen ganglioside GD2. Vaccination with monoclonal antibody 3F8 may stimulate a host cytotoxic…
A murine monoclonal antibody that recognizes CD7 (previously known as 3A1), a cell surface antigen expressed by most normal mature peripheral T…
A humanized murine monoclonal antibody (MoAb) against the 17-1A antigen, with potential adjuvant therapeutic properties in colorectal cancer. 17-1A antigen (EpCAM), a…
