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Monoclonal Antibody HuHMFG1
Definition 1
A humanized monoclonal antibody directed against MUC1, a mucin glycoprotein overexpressed in breast and other carcinomas. Monoclonal antibody HuHMFG1 stimulates antibody-dependent cell-mediated cytotoxicity (ADCC) against tumor cells expressing MUC1, resulting in a decrease in tumor burden. (NCI Thesaurus)
Definition 2
A monoclonal antibody that binds to the protein MUC1, which is found on breast, ovarian, pancreatic, gastric, and colon cancer cells. Monoclonal antibodies are made in the laboratory and can locate and bind to substances in the body, including cancer cells. HuHMFG1 is being studied in the treatment of some types of cancer. (NCI Dictionary)
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