| Health / Medical Topics |
Monoclonal Antibody LL2
A murine monoclonal antibody (MoAb) IgG2a, LL2. MoAb LL2 recognizes CD22, a B-lymphocyte-restricted antigen expressed as a cytoplasmic protein in progenitor B cells, and as a cell surface protein in mature B cells. When labeled with radioisotope, MoAb LL2 targets tumor cells that express CD22 antigen and delivers cytotoxic radiation that may be used to treat B-cell lineage cancers. (NCI Thesaurus)
YOU MAY ALSO LIKE
A murine IgG2a monoclonal antibody with potential antineoplastic activity. Monoclonal antibody L6 binds to the L6 antigen, a cell surface glycoprotein overexpressed…
Monoclonal recombinant antibody J591 (mAb HuJ591) recognizes the extracellular domain of prostate specific membrane antigen (PSMA), a cell surface peptidase highly expressed…
An anti-carcinoembryonic antigen (anti-CEA) murine monoclonal immunoglobulin G (IgG) with potential antineoplastic activity. CEA is overexpressed in several cancer cell types,…
A rat monoclonal antibody that inhibits Epidermal Growth Factor Receptor (EGFR), targeting tumor cells expressing the wild-type EGFR and EGFRvIII.
A humanized monoclonal antibody directed against the pancreatic cancer antigen MUC1 with potential antineoplastic activity. Monoclonal antibody HuPAM4 (mAb HuPAM4) binds to…
A humanized monoclonal antibody directed against vascular endothelial growth factor (VEGF), a pro-angiogenic cytokine. HuMV833 has been shown to decrease the…
