Health / Medical Topics

    Monoclonal Antibody SGN-14

    A humanized monoclonal antibody targeting the CD40 antigen with potential antineoplastic activity. CD-40, an integral membrane protein found on the surface of B lymphocytes and member of the tumor necrosis factor receptor super-family, is highly overexpressed on the cell surface of a number of B-cell malignancies. Monoclonal antibody SGN-14 specifically binds to and inhibits CD-40, thereby inhibiting cell proliferation and inducing cell lysis via antibody-dependent cellular cytotoxicity (ADCC) in cells. (NCI Thesaurus)




    YOU MAY ALSO LIKE

    A murine monoclonal antibody directed against the human epidermal growth factor receptor (EGFR). Monoclonal antibody RG 83852 binds to the EGFR,…
    A chimeric monoclonal antibody directed against a primate-restricted N-linked carbohydrate epitope (glycotope) expressed on various human carcinomas with potential antineoplastic activity. Following…
    An IgG murine monoclonal antibody directed against the ganglioside GD3 glycolipid, located in the cell membranes of some tumor cells. Monoclonal…
    The Monoclonal Antibody Production Shared Resource is responsible for monoclonal antibody generation and production, provides other antibody-related products and services to support…
    A recombinant monoclonal antibody (OVB3) directed against human ovarian cancer linked with an exotoxin derived from the bacterium Pseudomonas aeruginosa. The…
    A mouse monoclonal IgG3 antibody that reacts with the cytoplasm and cell surface of colonic adenocarcinoma and shows restricted normal tissue…

    © 1991-2023 The Titi Tudorancea Bulletin | Titi Tudorancea® is a Registered Trademark | Terms of use and privacy policy
    Contact