| Health / Medical Topics |
Mothers Against Decapentaplegic Homolog 4
The SMAD4 tumor suppressor protein specifically recognizes an eight base pair palindromic DNA sequence and is critical for transmitting TGFB, and related cytokine signals, to the cell nucleus to mediate transcriptional activation of target genes. The MADH4 gene is a cloned gene for Juvenile Polyposis, associated with colon cancer. (from OMIM 600993 and NCI) (NCI Thesaurus)
YOU MAY ALSO LIKE
Regulated by TGF-beta receptors, Mothers Against Decapentaplegic Homolog 3 is an effector of the TGF-beta response. MADH3 is associated with and…
Mothers against decapentaplegic homolog 2 (467 aa, ~52 kDa) is encoded by the human SMAD2 gene. This protein plays a role in…
Mothers against decapentaplegic homolog 1 (465 aa, ~52 kDa) is encoded by the human SMAD1 gene. This protein plays a role in…
The circuit board that contains most of the processor units.
The mother of your spouse.
A female parent.
