| Health / Medical Topics |
Mouse Glioblastoma
A high grade glial neoplasm consisting chiefly of undifferentiated anaplastic cells of glial origin that show marked nuclear pleomorphism. The diagnosis also depends on findings of tumor necrosis, and vascular endothelial proliferation. Frequently, tumor cells are arranged radially about an irregular focus of necrosis. These neoplasms grow rapidly, invade extensively and aggressively. (NCI Thesaurus/MMHCC)
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