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Mouse Myeloid Leukemia with Maturation
Comment: Leukemia in which neoplastic cells are moderately differentiated and neutrophilic; With a neutrophilic component; Without a monocytic component; greater or equal to 20% immature forms/blasts in hematopoietic tissue; less than or equal to 90% of non-lymphoid, non-erythroid hematopoietic cells in hematopoietic tissue are immature forms/blasts (NCI Thesaurus/MMHCC)
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Bone marrow cells are less than 50% erythroid cells; Bone marrow cells are less than 50% megakaryocytic cells; Comprised predominantly of granulocytic…
Comment: may be designated as having features of a named human MDS; Morphologic dysgranulopoiesis, dyserythropoiesis, and/or dysplastic megakaryocytes (with or without increased…
Comment: Leukemia in which neoplastic cells are well differentiated; less than 20% immature forms/blasts in hematopoietic tissue
A program to develop and refine experimental models that reflect the etiology and progression of human cancer.
A neoplastic disease of a mouse with clinical features sufficiently similar to those of a human cancer to serve as a test…
The use of special strains of mice to study a human disease or condition, and how to prevent and treat it. …
