| Health / Medical Topics |
Mouse Non-lymphoid Leukemia
A non-lymphoid hematopoietic neoplasm that diffusely involves hematopoietic tissue, generally both the spleen and bone marrow; Comment: Additional descriptor may be applied if appropriate: Acute; Comment: Additional descriptor may be applied if appropriate: Therapy Related; Comment: Additional descriptor may be applied if appropriate: With Multilineage Dysplasia; Disorder exhibits additional aspect of malignancy in appearance or behavior; Mice exhibit anemia, neutropenia, and/or thrombocytopenia; Neoplastic cells are disseminated; Non-lymphoid hematopoietic cells are increased in spleen (generally in both bone marrow and spleen) (NCI Thesaurus/MMHCC)
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Comment: Intended to be used for disorders of genetically engineered mice that are not characterized by increased blood counts; Genetic
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Comment: Intended to encompass diseases more closely related to human myelodysplastic/myeloproliferative or myeloproliferative diseases than to human myelodysplastic syndromes. Myeloid proliferations…
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Bone marrow cells are less than 50% erythroid cells; Bone marrow cells are less than 50% megakaryocytic cells; Comprised predominantly of granulocytic…
