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Mouse Pancreatic Intraepithelial Neoplasia-2
These mucinous epithelial lesions may be flat or papillary. These lesions must have some nuclear abnormalities including some loss of polarity, nuclear crowding, enlarged nuclei, pseudo-stratification and hyperchromatism. Mitoses are rare, but when present are non-luminal (not apical) and not atypical. (NCI Thesaurus/MMHCC)
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These epithelial lesions have a papillary, micropapillary or basally pseudostratified architecture, but are otherwise identical to PanIN-1A.
Flat epithelial lesions composed of tall columnar cells with basally located nuclei and abundant supranuclear mucin. The nuclei are small and round…
Based on IC of Rodent Tumors: The Mouse
A non-lymphoid hematopoietic neoplasm that diffusely involves hematopoietic tissue, generally both the spleen and bone marrow; Comment: Additional descriptor may be applied…
Bone marrow, if involved, contains at least focal areas in which hematopoiesis is preserved; Lesion is - invasive into surrounding tissues and/or…
Comment: Intended to be used for disorders of genetically engineered mice that are not characterized by increased blood counts; Genetic
