| Health / Medical Topics |
Mouse Pancreatic Intraepithelial Neoplasia-3
These are usually papillary or micropapillary, however, they may rarely be flat. True cribriforming, budding off of small clusters of epithelial cells into the lumen and luminal necroses. There is loss of nuclear polarity, dystrophic goblet cells (goblet cells with nuclei oriented towards the lumen and mucinous cytoplasm oriented toward the basement membrane), mitoses which may occasionally be abnormal, nuclear irregularities and prominent (macro) nucleoli. (NCI Thesaurus/MMHCC)
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These epithelial lesions have a papillary, micropapillary or basally pseudostratified architecture, but are otherwise identical to PanIN-1A.
Flat epithelial lesions composed of tall columnar cells with basally located nuclei and abundant supranuclear mucin. The nuclei are small and round…
Based on IC of Rodent Tumors: The Mouse
A non-lymphoid hematopoietic neoplasm that diffusely involves hematopoietic tissue, generally both the spleen and bone marrow; Comment: Additional descriptor may be applied…
Bone marrow, if involved, contains at least focal areas in which hematopoiesis is preserved; Lesion is - invasive into surrounding tissues and/or…
