Health / Medical Topics

    MSN wt Allele

    Human MSN wild-type allele is located in the vicinity of Xq11.1 and is approximately 74 kb in length. This allele, which encodes moesin protein, is involved in the modulation both of cell-cell adhesion and the structure of the cytoskeleton. A chromosomal translocation t(X;2)(q11;p23) of this gene and the ALK gene is associated with anaplastic large cell lymphoma. (NCI Thesaurus)




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