MTAP wt Allele

Human MTAP wild-type allele is located in the vicinity of 9p21 and is approximately 230 kb in length. This allele, which encodes S-methyl-5'-thioadenosine phosphorylase protein, is involved in the metabolism of both polyamines and purines. Mutation of the gene is associated with diaphyseal medullary stenosis with malignant fibrous histiocytoma. (NCI Thesaurus)

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MTAP Gene

This gene plays a role in purine salvage.

MTA3 Pathway

Approximately 30% of breast carcinomas lack ER expression. Presumably, these breast cancers become estrogen independent through genetic alterations that bypass the requirement…

MTA2 wt Allele

Human MTA2 wild-type allele is located within 11q12-q13.1 and is approximately 9 kb in length. This allele, which encodes metastasis-associated protein MTA2,…

MTA2 Gene

This gene plays a role in chromatin modification.

MTA1 wt Allele

Human MTA1 wild-type allele is located in the vicinity of 14q32.3 and is approximately 50 kb in length. This allele, which encodes…

MTA1 Gene

This gene plays a role in transcriptional regulation.