Health / Medical Topics |
MTRR wt Allele
Human MTRR wild-type allele is located in the vicinity of 5p15.31 and is approximately 55 kb in length. This allele, which encodes methionine synthase reductase protein, is involved in both B vitamin metabolism and methionine synthesis. Mutation of the gene is associated with both folate-sensitive neural tube defects and methylcobalamin deficiency type E. (NCI Thesaurus)
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