| Health / Medical Topics |
MUC16 wt Allele
Human MUC16 wild-type allele is located in the vicinity of 19q13.2 and is approximately 132 kb in length. This allele, which encodes mucin-16 protein, may play a role in the mediation of both cell adhesion and mucosal surface structural integrity. The gene is expressed aberrantly at elevated levels in ovarian cancers. (NCI Thesaurus)
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This gene is involved in both cellular adhesion and the maintenance of mucosal surfaces.
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