| Health / Medical Topics |
Multi-epitope Folate Receptor Alpha Peptide Vaccine
A peptide vaccine containing five immunogenic peptide epitopes of the human folate receptor alpha (FR alpha or FOLR1), including FR30, FR56, FR76, FR113, and FR238, with potential immunomodulating and antineoplastic activity. Upon administration, the multi-epitope FR alpha peptide vaccine may induce a cytotoxic T-lymphocyte (CTL) response against FR alpha-overexpressing tumor cells. FR alpha is a high-affinity folate-binding protein and a member of the folate receptor family; this receptor is overexpressed in a majority of ovarian cancers and in about 50% of breast cancers. (NCI Thesaurus)
YOU MAY ALSO LIKE
A microorganism, often a bacterium, that is not susceptible to standard antimicrobial therapies.
Cancer cells resistant to a diverse set of hydrophobic drugs are known as MDR cells (multidrug-resistant). Large membrane proteins overproduced in MDR…
A static light scattering technique involving measurement of the amount of light scattered by a suspension at multiple angles relative to the…
A method for simultaneous detection of multiple target molecules. It utilizes specific antibodies for the analytes of interest coupled to fluorescent polystyrol…
An orally available, small molecule inhibitor of AGC group kinases, with potential antineoplastic activity. AT13148 inhibits, in an ATP-competitive manner, the enzymatic…
A vial intended to contain more than one dose of the drug product.
