| Health / Medical Topics |
Multidrug Resistance-Associated Protein 4
Multidrug resistance-associated protein 4 (1325 aa, ~150 kDa) is encoded by the human ABCC4 gene. This protein plays a role in platelet degranulation, ATP hydrolysis and organic anion transport. (NCI Thesaurus)
YOU MAY ALSO LIKE
Simultaneous resistance to a spectrum of unrelated drugs following exposure to a single agent. Mechanisms involve expression of multidrug efflux pumps (p-glycoprotein),…
A drug that makes tumor cells more sensitive to the effects of chemotherapy.
Treatment used to make cancer cells less resistant to anticancer drugs.
Multidrug Resistance Induction involves initiation of activities of biologic molecules or complexes involved in processes that increase the ability of cancer cells…
Mammalian P-glycoproteins are encoded by the MDR gene family and belong to the ATP-binding cassette vectorial transport protein class; the CFTR chloride…
Adaptation of tumor cells to anticancer drugs in ways that make the drugs less effective.
