Health / Medical Topics |
Multiple Organ Failure
Definition 1
Complete impairment of two or more organs or organ systems. (NCI Thesaurus)
Definition 2
A disorder characterized by progressive deterioration of the lungs, liver, kidney and clotting mechanisms. (NCI Thesaurus/CTCAE)
Definition 3
A progressive condition usually characterized by combined failure of the lungs, liver, kidney, and clotting mechanisms. (Food and Drug Administration)
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Only the light chain (kappa or lambda) of the immunoglobulin is defective.
The heavy chain, IgM, of the immunoglobulin is defective. This finding is seen in other lymphocytic/plasmacytic disorders as well, including Waldenstrom…
The heavy chain, IgG, of the immunoglobulin is defective. This is the most common type of multiple myeloma (>50%).
The heavy chain of the immunoglobulin, IgE, is defective. This multiple myeloma subtype is extremely rare.
The heavy chain of the immunoglobulin, IgD, is defective. This multiple myeloma subtype is very rare (~1%).