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MUTAGENIC
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I. (adjective)
Sense 1
Meaning:
Capable of inducing mutation (used mainly of extracellular factors such as X-rays or chemical pollution)
Classified under:
Relational adjectives (pertainyms)
Pertainym:
mutagen (any agent (physical or environmental) that can induce a genetic mutation or can increase the rate of mutation)
Context examples:
Acute myeloid leukemias and myelodysplastic syndromes arising as a result of the mutagenic effect of alkylating agents that are used for the treatment of malignant tumors.
(Alkylating Agent-Related Acute Myeloid Leukemia and Myelodysplastic Syndrome, NCI Thesaurus)
It is also mutagenic, teratogenic, and causes immunosuppression in animals.
(Aflatoxin B1, NLM, Medical Subject Headings)
A benzopyrene derivative with carcinogenic and mutagenic activity.
(Benzo(a)pyrene-7,8-diol 9,10-Epoxide, NLM, Medical Subject Headings)
Used as a topical treatment for skin hyperpigmentation and in various cosmetic products, it is metabolized mainly to glutathione conjugates and forms mutagenic DNA adducts in in-vitro systems.
(Hydroquinone, NCI Thesaurus)
Methyleugenol is mutagenic in animals and is reasonably anticipated to be a human carcinogen based on evidence of carcinogenicity in animals.
(Methyleugenol, NCI Thesaurus)
Any transmissible change in the genetic material of an organism, which can result from radiation, viral infection, transposition, treatment with mutagenic chemicals and errors during DNA replication or meiosis.
(Mutation, NCI Thesaurus)
An in vivo assay test used to determine if an agent, such as a chemical, is capable of causing mutations in living organisms, and if so, the strength of its mutagenic activity.
(Ames Assay, NCI Thesaurus)
A nitrosourea compound with alkylating, carcinogenic, and mutagenic properties.
(Methylnitrosourea, NLM, Medical Subject Headings)
Furan is mutagenic in animals and is reasonably anticipated to be a human carcinogen based on evidence of carcinogenicity in experimental animals.
(Furan, NCI Thesaurus)
Cobalt sulfate is mutagenic in mammalian cells and is reasonably anticipated to be a human carcinogen based on evidence of carcinogenicity in experimental animals.
(Cobaltous Sulfate, NCI Thesaurus)
