MutS Homolog 4

MutS Homolog 4, a 105-kD protein encoded by the MSH4 gene, belongs to the DNA mismatch repair muts family and is involved in meiotic recombination. It is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis. The human MSH4 transcripts are detectable only in testis and in ovary with a lower level of expression. (From LocusLink, OMOM, Swiss_Prot) (NCI Thesaurus)

YOU MAY ALSO LIKE

Mutation Spectra

The range of mutations that have occurred to a gene, or at a specific locus.

Mutation Fixation

In avoiding recognition and removal by the mismatch repair system, a Mutation Fixation involves stabilization of a DNA sequence alteration in both…

Mutation Detection

The detection by physical, chemical, or biological means of an altered DNA sequence. Includes SSCP, DNA sequencing, hybridization, and reporter gene…

Mutation carrier

A person who has a mutated (changed) copy of a gene. This change may cause a disease in that person or in…

Mutation Analysis

A procedure to test for the presence of a specific mutation or a set of mutations as opposed to complete gene sequencing…

Mutation Abnormality

Any transmissible change in the genetic material of an organism, which can result from radiation, viral infection, transposition, treatment with mutagenic chemicals…