| Health / Medical Topics |
MYC-Family Oncogene
Variants of proto-oncogenes that are members of the MYC family of early response genes, which encode regulatory proteins that act as homo- or hetero-dimers. These aberrant genes are activated by mutations or amplification, resulting in overexpression of the protein products. This can cause uncontrolled cell proliferation. (NCI Thesaurus)
YOU MAY ALSO LIKE
Human MYC wild-type allele is located in the vicinity of 8q24.21 and is approximately 5 kb in length. This allele, which encodes…
Myc proto-oncogene protein (439 aa, ~49 kDa) is encoded by the human MYC gene. This protein plays a role in the regulation…
This gene plays a role in cell cycle progression and apoptosis. Cytogenetic aberrations in the gene are involved in cellular transformation and…
MYC family proteins exhibit sequence homology with the transcription factor MYC protooncogene.
MYC Family Genes encode MYC Family Proteins, class III bHLH leucine zipper transcription factors having cellular proliferative and apoptotic roles. Dimerization via…
MYC boxes I and II, found in the N termini of all members of the MYC protein family, function to direct the…
