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Myeloablative chemotherapy
Pronunciation
Definition 1
High-dose chemotherapy that kills cells in the bone marrow, including cancer cells. It lowers the number of normal blood-forming cells in the bone marrow, and can cause severe side effects. Myeloablative chemotherapy is usually followed by a bone marrow or stem cell transplant to rebuild the bone marrow. (NCI Dictionary)
Definition 2
The administration of high-dose chemotherapy, with or without total body irradiation, to eradicate the underlying disease and/or ablate the immune system of the patient. (NCI Thesaurus)
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