Nabilone

Pronunciation

Definition 1

A synthetic pill form of an active chemical in marijuana called delta-9-tetrahydrocannabinol (THC). Nabilone is used to treat nausea and vomiting caused by chemotherapy in patients who have not been helped by other therapy. It is a type of cannabinoid. Also called Cesamet. (NCI Dictionary)

Definition 2

A synthetic cannabinoid and dibenzopyrane derivative with anti-emetic activity. Although the mechanism of action has not been fully elucidated yet, it has been suggested that nabilone is a highly selective and strong agonist for the cannabinoid receptors CB1 and CB2, both of which are coupled to Gi/o proteins. The CB1 receptors are expressed predominantly in central and peripheral neurons and receptor stimulation has been implicated in the reduction of chemotherapy-induced nausea. (NCI Thesaurus)

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