Health / Medical Topics |
NCOA4/RET Fusion Protein
A fusion protein encoded by the NCOA4/RET fusion gene. This protein is comprised of approximately 240 N-terminal amino acids of the nuclear receptor coactivator 4 protein, fused with most of the C-terminal cytoplasmic domain of the proto-oncogene tyrosine-protein kinase receptor Ret protein, including the tyrosine kinase domain. (NCI Thesaurus)
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A fusion gene that results from a paracentric inversion inv(10)(q11q11) which fuses the 5' portion of the NCOA4 gene and the 3'…
Human NCOA4 wild-type allele is located in the vicinity of 10q11.2 and is approximately 25 kb in length. This allele, which encodes…
This gene is involved in the transcriptional activation of target genes.
Human NCOA3 wild-type allele in the vicinity of 20q12 is approximately 155 kb in length. This allele, which encodes nuclear receptor coactivator…
This gene plays a role in regulation of transcription.
Human NCOA2 wild-type allele is located in the vicinity of 8q13.2 and is approximately 292 kb in length. This allele, which encodes…