Health / Medical Topics

    NCOA4/RET Fusion Protein

    A fusion protein encoded by the NCOA4/RET fusion gene. This protein is comprised of approximately 240 N-terminal amino acids of the nuclear receptor coactivator 4 protein, fused with most of the C-terminal cytoplasmic domain of the proto-oncogene tyrosine-protein kinase receptor Ret protein, including the tyrosine kinase domain. (NCI Thesaurus)




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    Human NCOA2 wild-type allele is located in the vicinity of 8q13.2 and is approximately 292 kb in length. This allele, which encodes…

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