Health / Medical Topics

    NDN wt Allele

    Human NDN wild-type allele is located within 15q11.2-q12 and is approximately 2 kb in length. This allele, which encodes necdin protein, is involved in suppression of cell growth in postmitotic neurons. Mutations in this gene are associated with Prader-Willi syndrome. (NCI Thesaurus)




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