Negative Regulation of Degradation of Complement

Complement Stabilization inhibits conjugation, transport, oxidation, or proteolysis of complement system proteins; sequentially interacting serum proteins (some serine proteases), their receptors, and related regulatory proteins. Activated by cell-surface bound antibody, immune complexes, or a microbial membrane carbohydrate, complex complement cascades (classical or properdin pathway) generate Membrane Attack Complex, which creates target cell wall pores and lysis. The complement system also plays a role in antibody-dependent cytolysis, anaphylaxis, phagocytosis, opsonization, chemotaxis, and hemolysis. (NCI Thesaurus)

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Negative Regulation of Degradation of Antibody

Antibody Stabilization inhibits conjugation, transport, oxidation, or proteolysis of a class of cell-surface or secreted B lymphocyte proteins that non-covalently interact through…

Negative Regulation of Degradation of Adhesion Factor

Adhesion Factor Stabilization inhibits conjugation, transport, oxidation, or proteolysis of cell surface proteins involved in cell-cell or cell-matrix attachment. Such stabilization can…

Negative Regulation of Cytolytic Process

Any process that decreases the frequency, rate or extent of cytolysis.

Negative Regulation of Complement Activation

Any physiologic process in which the C3 and C5 convertases are disassembled or proteolytically inactivated, limiting the persistence of convertase activity. This…

Negative Regulation of Coagulation

Events or activities that prevent or inhibit coagulation.

Negative Regulation of Cell-Matrix Adhesion

Any cellular process that reduces the frequency, rate or extent of adhesion between cells and the underlying extracellular matrix.