Health / Medical Topics |
Negative Regulation of G0 to G1 Transition
G0 to G1 Phase Arrest consists of interference with, or restraint of, activities that regulate cellular capability to transition from the resting stage (between successive cell divisions) and the initial phase of the cell cycle (Gap 1 phase), preceding DNA synthesis. G1 subphases include competence, entry (G1a), progression (G1b), and assembly (G1c), based on effects of limiting growth factors, nutrients, or inhibitors. (NCI Thesaurus)
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