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NEPHRON
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
Any of the small tubules that are the excretory units of the vertebrate kidney
Synonyms:
Classified under:
Hypernyms ("nephron" is a kind of...):
tubule (a small tube)
Meronyms (parts of "nephron"):
malpighian body; malpighian corpuscle; renal corpuscle (the capsule that contains Bowman's capsule and a glomerulus at the expanded end of a nephron)
Holonyms ("nephron" is a part of...):
kidney (either of two bean-shaped excretory organs that filter wastes (especially urea) from the blood and excrete them and water in urine)
Context examples:
A nephron in which the renal corpuscle is in close proximity to the renal medulla while the proximal convoluted tubule and loop of Henle are located much deeper in the kidney.
(Juxtamedullary Nephron, NCI Thesaurus)
The last part of a long, twisting tube that collects urine from the nephrons (cellular structures in the kidney that filter blood and form urine) and moves it into the renal pelvis and ureters.
(Collecting duct, NCI Dictionary)
Aldosterone plays a major role in sodium and potassium metabolism by binding to epithelial mineralocorticoid receptors (MR) in the renal collecting duct cells localized in the distal nephron, promoting sodium resorption and potassium excretion.
(Aldosterone-Regulated Sodium Reabsorption Pathway, NCI Thesaurus/KEGG)
Most kidney diseases attack the nephrons.
(Kidney Diseases, NIH: National Institute of Diabetes and Digestive and Kidney Diseases)
To test the functionality of the new structures, the team used Dextran — a fluorescent protein which stains the urine-like substance produced when nephrons filter the blood, called glomerular filtrate.
(Scientists Create Functioning Kidney Tissue, The Titi Tudorancea Bulletin)
Sodium transport across the tight epithelia of Na+ reabsorbing tissues such as the distal part of the kidney nephron and colon is the major factor determining total-body Na+ levels, and thus, long-term blood pressure.
(Aldosterone-Regulated Sodium Reabsorption Pathway, NCI Thesaurus/KEGG)
Chronic kidney disease damages the nephrons slowly over several years.
(Kidney Diseases, NIH: National Institute of Diabetes and Digestive and Kidney Diseases)
The new structures contained most of the constituent parts present in human nephrons — including proximal tubules, distal tubules, Bowman's capsule and Loop of Henle.
(Scientists Create Functioning Kidney Tissue, The Titi Tudorancea Bulletin)
