| Health / Medical Topics |
Neuroendocrine Differentiation
A morphological appearance characteristic of invasive carcinomas in which there is focal or extensive transformation (metaplasia) of nests of malignant epithelial cells into cells which resemble neurosecretory cells morphologically, immunohistochemically, and by electron microscopy. (NCI Thesaurus)
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Proliferation of the neuroendocrine cells isolated to the base of the crypts. Cells retain normal architecture. Proliferating cells are mixed with other…
An endocrine cell that produces and releases hormones and regulatory proteins such as neurotransmitters and neuropeptide hormones. This type of cell enables…
A rare type of cancer that forms on or just beneath the skin, usually in parts of the body that have been…
This is a composite group consisting of tumors, in which neuroendocrine differentiation has been confirmed by immunohistochemical detection of such proteins as…
A malignant neuroendocrine neoplasm composed of cells containing secretory granules that stain positive for NSE and chromogranin. The neoplastic cells are…
Neoplasm is isolated to two crypts in size.
