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Nimotuzumab
Pronunciation
Definition 1
A monoclonal antibody being studied in the treatment of some types of cancer. Monoclonal antibodies are made in the laboratory and can locate and bind to substances in the body, including cancer cells. Nimotuzumab binds the epidermal growth factor receptor (EGFR) and blocks cancer cells that depend on epidermal growth factor for growth. Also called Theraloc. (NCI Dictionary)
Definition 2
A humanized monoclonal antibody directed against the epidermal growth factor receptor (EGFR) with potential antineoplastic activity. Nimotuzumab binds to and inhibits EGFR, resulting in growth inhibition of tumor cells that overexpress EGFR. This agent may act synergistically with radiation therapy. (NCI Thesaurus)
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