Health / Medical Topics

    NLRP1 wt Allele

    Human NLRP1 wild-type allele is located in the vicinity of 17p13.2 and is approximately 120 kb in length. This allele, which encodes NACHT, LRR and PYD domains-containing protein 1, is involved in apoptosis induction. Mutations in the gene are associated with vitiligo-associated multiple autoimmune disease susceptibility 1. (NCI Thesaurus)




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