| Health / Medical Topics |
NOTCH1 wt Allele
Human NOTCH1 wild-type allele is located in the vicinity of 9q34.3 and is approximately 51 kb in length. This allele, which encodes neurogenic locus notch homolog protein 1 protein, plays a role in developmental processes by controlling cell fate decisions. (NCI Thesaurus)
YOU MAY ALSO LIKE
This gene is involved in intercellular signal transduction that plays a key role in development.
The Notch signaling pathway is an evolutionarily conserved, intercellular signaling mechanism essential for proper embryonic development in all metazoan organisms in the…
The free carboxy-terminal intracellular domain (ICD) of a notch family protein, which is a product of regulated intramembrane proteolysis mediated by the…
Notch is a large cell-surface receptor that is activated by contact with membrane-bound ligands on neighboring cells. The ligands that activate…
Expressed in adult/fetal tissues by human NOTCH1 Gene (Notch Family), 2556-aa 273-kDa phosphorylated type 1 transmembrane Notch Homolog 1 contains 36 extracellular…
Presenilin-1 (PS1) is associated with gamma secretase activity that cleaves amyloid precursor protein (APP) and is implicated in Alzheimer's disease. Presenilin-1…
